The Eastern church gives little evidence of particular interest in the book of Revelation. Oecumenius of Isauria's commentary on the book is the earliest full treatment in Greek and dates only from the early sixth century. Along with Oecumenius's commentary, only that of Andrew of Caesarea (dating from the same era and often summarizing Oecumenius before offering a contrary opinion) and that of Arethas of Caesarea four centuries later provide any significant commentary from within the Greek tradition.

William Weinrich renders a particular service to readers interested in ancient commentary on the Apocalypse by translating in one volume the two early sixth-century commentaries. Because of the two interpreters' often differing understandings, readers are exposed not only to early dialogue on the meaning and significance of the book for the faith and life of the church, but also to breadth of interpretation within the unity of the faith the two shared.